Genome informatics and personalized medicine.
نویسندگان
چکیده
منابع مشابه
Informatics research to enable clinically relevant, personalized genomic medicine
This is a particularly exciting issue of JAMIA. Not only do we display exceptional work spanning informatics research that integrates data from different biological levels (from molecules to tissues to individuals), but we also show how this research is greatly enhanced by clever integration of knowledge from publicly shared resources (from nucleotide sequences to gene and protein networks to d...
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One of the most important areas for the application of genomic science and technology is said to be personalized medicine (which is often called tailor-made medicine in Japan). Personalized medicine is an idealized medical practice aiming to give the right drugs to the right patients at the right times. It has been widely admitted that many projects for finding Single nucleotide polymorphisms (...
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It is indeed exciting to work in a field where challenges evolve rapidly and continuously. This is the privilege of disciplines, such as ours, that lie at the intersection of many scientif ic and societal domains. As physical and digital aspects of our lives mingle increasingly, the prospect of informatics making a real difference to health outcomes and healthcare processes becomes ever more re...
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In genome-wide association studies (GWAS), researchers analyze the genetic variation across the entire human genome, searching for variations that are associated with observable traits or certain diseases. There are several inference challenges in GWAS, including the huge number of genetic markers to test, the weak association between truly associated markers and the traits, and the correlation...
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The review is devoted to the impact of human genome research on progress in modern medicine. Basic achievements in genome research have resulted in the deciphering of the human genome and creation of a molecular landmarks map of the human haploid genome (HapMap Project), which has made a tremendous contribution to our understanding of common genetic and multifactorial (complex) disorders. Curre...
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ژورنال
عنوان ژورنال: Drug Delivery System
سال: 2003
ISSN: 1881-2732,0913-5006
DOI: 10.2745/dds.18.51